Journal of Cardiothoracic and Vascular Anesthesia
Volume 22, Issue 5 , Pages 675-680 , October 2008

Monitoring Recombinant Factor VIIa Treatment: Efficacy Depends on High Levels of Fibrinogen in a Model of Severe Dilutional Coagulopathy

Presented in part at the annual meeting of the American Society of Anesthesiologists, Chicago, IL, October 15-17, 2006.

  • Michael T. Ganter, MD

      Affiliations

    • Institute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland
  • ,
  • Saskia Schmuck, MD

      Affiliations

    • Institute of Anesthesiology and Intensive Care Medicine, Triemli City Hospital, Zurich, Switzerland
  • ,
  • Christine R. Hamiel, BS

      Affiliations

    • Department of Anesthesiology, University of Colorado Health Sciences Center, Denver, CO
  • ,
  • Paul E. Wischmeyer, MD

      Affiliations

    • Department of Anesthesiology, University of Colorado Health Sciences Center, Denver, CO
  • ,
  • Daniela Heule, MD

      Affiliations

    • Institute of Anesthesiology and Intensive Care Medicine, Triemli City Hospital, Zurich, Switzerland
  • ,
  • Andreas Zollinger, MD

      Affiliations

    • Institute of Anesthesiology and Intensive Care Medicine, Triemli City Hospital, Zurich, Switzerland
  • ,
  • Christoph K. Hofer, MD

      Affiliations

    • Institute of Anesthesiology and Intensive Care Medicine, Triemli City Hospital, Zurich, Switzerland
    • Corresponding Author InformationAddress reprint requests to Christoph K. Hofer, MD, Institute of Anesthesiology and Intensive Care Medicine, Triemli City Hospital Zurich, Birmensdorferstr 497, 8063 Zurich, Switzerland

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 M.T. Ganter and S. Schmuck contributed equally to this work.

 Supported by Pentapharm GmbH (Munich, Germany), Sienco Inc (Arvada, CO), and Novo Nordisk (Cophenhagen, Denmark). An educational grant for this study was provided by ZLB Behring (Berne, Switzerland). None of the authors is related to or has financial interests in the manufacturers of products studied.

PII: S1053-0770(08)00023-2

doi: 10.1053/j.jvca.2008.01.017

Journal of Cardiothoracic and Vascular Anesthesia
Volume 22, Issue 5 , Pages 675-680 , October 2008