Journal of Cardiothoracic and Vascular Anesthesia
Volume 22, Issue 5 , Pages 693-698 , October 2008

Levosimendan in Aortic Valve Surgery: Cardiac Performance and Recovery

  • Kati Järvelä, MD, PhD

      Affiliations

    • Heart Center, Pirkanmaa Hospital District, Tampere, Finland
    • Department of Anesthesia, Tampere University Hospital, Tampere, Finland
    • Corresponding Author InformationAddress reprint requests to Kati Järvelä, MD, PhD, Heart Center, Pirkanmaa Hospital District, PO Box 2000, FI-33521 Tampere, Finland
    • ,
  • Pasi Maaranen, MD

      Affiliations

    • Heart Center, Pirkanmaa Hospital District, Tampere, Finland
    • ,
  • Tero Sisto, MD, PhD

      Affiliations

    • Heart Center, Pirkanmaa Hospital District, Tampere, Finland
    • ,
  • Esko Ruokonen, MD, PhD

      Affiliations

    • Department of Intensive Care, Kuopio University Hospital, Kuopio, Finland

References 

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  14. Varpula M, Karlsson S, Ruokonen E, et al. Mixed venous saturation cannot be estimated by central venous oxygen saturation in septic shock. Intensive Care Med. 2006;32:1336–1343
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  18. O′Connor CM, Gattis WA, Uretsky BF, et al. Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: Insights from the Flolan International Randomized Survival Trial (FIRST). Am Heart J. 1999;138:78–86
  19. Yokoshiki H, Katsube Y, Sunagawa M, et al. Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes. Eur J Pharmacol. 1997;333:249–259
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  26. De Hert SG, Lorsomradee S, Cromheecke S, et al. The effects of levosimendan in cardiac surgery patients with poor left ventricular function. Anesth Analg. 2007;1004:766–773
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  28. Varadajan SG, An J, Novalija E, et al. Sevoflurane before or after ischemia improves contractile and metabolic function while reducing myoplasmic Ca2+ loading in intact hearts. Anesthesiology. 2002;96:125–133
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PII: S1053-0770(08)00030-X

doi: 10.1053/j.jvca.2008.01.024

Journal of Cardiothoracic and Vascular Anesthesia
Volume 22, Issue 5 , Pages 693-698 , October 2008

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