Journal of Cardiothoracic and Vascular Anesthesia
Volume 23, Issue 1 , Pages 41-47, February 2009

Methemoglobin Effects on Coagulation: A Dose-Response Study With HBOC-200 (Oxyglobin) in a Thrombelastogram Model

  • Mojgan Moallempour, MD

      Affiliations

    • Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, CA
  • ,
  • Jonathan S. Jahr, MD

      Affiliations

    • Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, CA
    • Corresponding Author InformationAddress reprint requests to Jonathan S. Jahr, MD, Department of Anesthesiology, David Geffen School of Medicine at UCLA, CHS 56-122, Box 951778, 650 Charles E. Young Drive South, Los Angeles, CA 90095
  • ,
  • Jennifer C. Lim

      Affiliations

    • Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, CA
  • ,
  • David Weeks, PhD, MD

      Affiliations

    • Department of Anesthesiology, University of California, San Francisco, San Francisco, CA
  • ,
  • Anthony Butch, PhD

      Affiliations

    • Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
  • ,
  • Bernd Driessen, DVM, PhD

      Affiliations

    • Department of Clinical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA

published online 01 September 2008.

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 J.S.J. was a principle investigator in a phase 2 and phase 3 study with Biopure. Veterinary product Oxyglobin was purchased at Veterinary Pharmacy for the purposes of this study.

PII: S1053-0770(08)00182-1

doi:10.1053/j.jvca.2008.06.006

Journal of Cardiothoracic and Vascular Anesthesia
Volume 23, Issue 1 , Pages 41-47, February 2009