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Abstract
During the insertion of an automatic implantable cardioverter defibrillator, repeated
induction of ventricular tachycardia or ventricular fibrillation and subsequent defibrillation
is performed to determine the defibrillation threshold. In this study, the influence
of these testing episodes on myocardial function was investigated in 13 patients under
general anesthesia. Preoperative ejection fraction (EF) was 41 (14 to 84)% (median
and range). Testing was performed 3 (2–5) times. During these testing episodes the
patients received a total of 4 (2–8) countershocks. Patients with a preoperative EF
< 30% (N = 5) showed a significant reduction of cardiac index (CI) from 2.2 (1.5-3.3)
L/min/m2 before testing to 1.5 (1.3-2.3) L/min/m2 after the last testing episode, and of left ventricular stroke work index (LVSWI)
from 32 (14–53) g · m/m2 before testing to 22 (7–43) after the last testing episode. These changes were not
related to the total fibrillation time or the cumulative defibrillation energy. Patients
with a preoperative EF > 30% (N = 8) showed no significant changes of CI (2.15 [1.8-3.0]
L/min/ m2v 2.15 [1.7-3.0] L/ min/ m2) or LVSWI (35 [28–48] g · m/m2v 33.5 [27–52] g · m/m2). Comparison of the two patient groups revealed similar hemodynamic
baseline values, but significant differences in LVSWI after the last testing episode.
Defibrillation testing may produce a further reduction in myocardial performance in
patients with preexisting poor cardiac function.
Keywords
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© 1993 Published by Elsevier Inc.