CARDIOVASCULAR DISEASE (CVD) is now the leading cause of death worldwide, and heart
failure accounts for a significant portion of this mortality.
In the United States, the prevalence of heart failure is estimated at 5.8 million,
about 670,000 new cases are diagnosed annually, and the current estimated direct and
indirect cost for heart failure care is $39.2 billion.
In the United States, the “baby boom” generation is now entering the age range when
heart failure becomes much more common, and, worldwide, dietary and lifestyle changes
have increased dramatically the prevalence of CVD. With these population prevalence
changes, the proportion of CVD mortality attributable to end-stage heart failure will
only continue to increase because the prospect for definitive therapies are absent.
Key words
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Article info
Publication history
Published online: April 14, 2011
Footnotes
Gerard R. Manecke, Jr, MD
Marco Ranucci, MD
Section Editors
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.