Objectives
Design
Setting
Participants
Interventions
Measurements and Main Results
Conclusion
Key Words
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STS Adult Cardiac Surgery Database. Available at: http://www.sts.org/sites/default/files/documents/2012-AC-4thHarvestExecutiveSummary.pdf. Accessed September 2017.
- A prospective observational cohort study to identify the causes of anaemia and association with outcome in cardiac surgical patients.Heart. 2015; 101: 107-112
- Risk associated with preoperative anemia in cardiac surgery: A multicenter cohort study.Circulation. 2008; 117: 478-484
- Preoperative anemia increases mortality and postoperative morbidity after cardiac surgery.J Cardiothorac Surg. 2014; 9: 137
- Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Transfusion reactions: Prevention, diagnosis, and treatment.Lancet. 2016; 388: 2825-2836
- A randomized controlled pilot study of adherence to transfusion strategies in cardiac surgery.Transfusion. 2012; 52: 91-99
Transfusion Requirements in Cardiac Surgery II. Available at: http://clinicaltrials.gov/ct2/show/NCT01484639?term=red+cell+transfusion+and+cardiac+surgery&rank=1.
- Validation of European System for Cardiac Operative Risk Evaluation (EuroSCORE) in North American cardiac surgery.Eur J Cardiothorac Surg. 2002; 22: 101-105
- Risk stratification in heart surgery: Comparison of six score systems.Eur J Cardiothorac Surg. 2000; 17: 400-406
- The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery.Anesth Analg. 2009; 108: 1741-1746
- Factors affecting transfusion of fresh frozen plasma, platelets, and red blood cells during elective coronary artery bypass graft surgery.Arch Pathol Lab Med. 2003; 127: 415-423
- Factors affecting perioperative transfusion decisions in patients with coronary artery disease undergoing coronary artery bypass surgery.Anesthesiology. 2006; 105: 19-27
- Identifying patients at risk of intraoperative and postoperative transfusion in isolated CABG: Toward selective conservation strategies.Ann Thor Surg. 2004; 78: 1547-1555
- Risk factors for red cell transfusion in adults undergoing coronary artery bypass surgery: A systematic review.Vox Sang. 2007; 93: 1-11
- Randomization in clinical trials of titrated therapies: Unintended consequences of using fixed treatment protocols.Crit Care Med. 2007; 35: 1509-1516
- CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials.Ann Intern Med. 2010; 152: 726-732
- Perioperative blood transfusion and blood conservation in cardiac surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline.Ann Thorac Surg. 2007; 83: S27-S86
- Human cardiovascular and metabolic response to acute severe isovolemic anemia.JAMA. 1998; 279: 217-221
- Is a low transfusion threshold safe in critically ill patients with cardiovascular diseases?.Crit Care Med. 2001; 29: 227-234
- Third universal definition of myocardial infarction.Circulation. 2012; 126: 2020-2035
- KDIGO Clinical Practice Guideline for Acute Kidney Injury.Kidney Int Suppl. 2012; 2: 1-138
Confusion Assessment Method for the ICU (CAM-ICU) Available at: http://www.icudelirium.org/docs/CAM_ICU_training.pdf. Accessed August 2017.
Intensive Care Delirium Screening Checklist (ICDSC). Available at: http://www.lhsc.on.ca/Health_Professionals/CCTC/elearning/bedside_sheets_CCTC_icdsc.pdf. Accessed August 2017.
- Morbidity and duration of ICU stay after cardiac surgery. A model for preoperative risk assessment.Chest. 1992; 102: 36-44
- Stratification of morbidity and mortality outcome by preoperative risk factors in coronary artery bypass patients. A clinical severity score.JAMA. 1992; 267: 2344-2348
- Transfusion triggers for guiding RBC transfusion for cardiovascular surgery: A systematic review and meta-analysis.Crit Care Med. 2014; 42: 2611-2624
- Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): A randomised, double-blind, placebo-controlled trial.Lancet. 2015; 386: 1243-1253
- Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery.Annals Cardiac Anesth. 2008; 11: 15-19
- The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery.Anesth Analg. 2009; 108: 1741-1746
- Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: Effect on patient outcome.Transfusion. 1999; 39: 1070-1077
- An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusions.Transfusion. 2010; 50: 2738-2744
- Lessons from and cautions about noninferiority and equivalence randomized trials.JAMA. 2006; 295: 1172-1174
- A multicenter, randomized controlled clinical trial of transfusion requirements in critical care.N Engl J Med. 1999; 340: 409-417
- Liberal or restrictive transfusion in high-risk patients after hip surgery.N Engl J Med. 2011; 365: 2453-2462
- Red blood cell transfusion for people undergoing hip fracture surgery.Cochrane Database of Systematic Reviews. 2015; (CD009699): 4
- Liberal or restrictive transfusion after cardiac surgery.N Engl J Med. 2015; 372: 997-1008
- Nadir hematocrit during cardiopulmonary bypass: End-organ dysfunction and mortality.J Thorac Cardiovasc Surg. 2012; 144: 654-662
Article info
Publication history
Footnotes
The study was supported by the Canadian Institutes of Health Research, Canadian Blood Services, the National Health and Medical Research Council of Australia, and the Health Research Council of New Zealand. Nadine Shehata is supported by the Canadian Blood Services/Canadian Institute of Health Research New Investigator Award. C. David Mazer is supported by a Merit Award from the Department of Anesthesia, St. Michael’s Hospital, University of Toronto