BLEEDING is a well-documented and frequently encountered complication after cardiac
surgery, affecting roughly 2%-to-10% of all patients.
1
Major bleeding is a known risk factor for significant morbidity and mortality after
complex cardiac surgery such as aortic surgery, left ventricular assist device implantation,
redo sternotomy, and transplant.
2
The definition of major hemorrhage remains controversial; however, most agree that
bleeding requiring reoperation, transfusion, or significant decreases in hemoglobin
should qualify. Numerous prophylactic agents have been studied for the reduction of
bleeding and/or the need for transfusion. In this review, the authors examine the
use of fresh frozen plasma (FFP) for priming the cardiopulmonary bypass (CPB) circuit
and discuss the lack of evidence supporting its routine use in this population.Key Words
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Publication history
Published online: May 19, 2021
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