Introduction
To investigate the effects of perioperative glycemic variability on postoperative
acute kidney injury after off-pump coronary artery bypass grafting
Methods
Acute kidney injury (AKI) was defined by Kidney Disease Improving Global Outcomes
(KDIGO) criteria. Glycemic variability was measured by Maximal blood glucose difference
(MGD). The MGD was analyzed as quartiles and all patients were divided into four groups.
Group 1: MGD < 5.4 mmol/L, Group 2: MGD 5.4-7.1 mmol/L, Group 3: MGD 7.1-9.1 mmol/L,
Group 4: MGD > 9.1 mmol/L.
Results
1,426 patients underwent OPCABG were analyzed. Postoperative AKI developed in 338
patients (28.1%). The incidence of overall AKI in four groups was 22%, 22%, 29% and
40%, respectively. It was higher in group 3 to 4 than group 1 to 2 and higher in group
4 than group 3(P<0.05). The incidence of AKI stage II and III was higher in group
4 than Group1 to 3. The length of postoperative ICU intubation, stay and hospitalization
was significantly longer in group 4 than those in the lower three MGD Groups.
Discussion
Increased glycemic variability is significantly associated with the risk of postoperative
AKI after OPCABG.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Cardiothoracic and Vascular AnesthesiaAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Identification
Copyright
© 2021 Published by Elsevier Inc.
