This special article focuses on the highlights in cardiothoracic transplantation literature
in the year 2020. Part I encompasses the recent literature on lung transplantation,
including the advances in preoperative assessment and optimization, donor management,
including the use of ex-vivo lung perfusion, recipient management, including those
who have been infected with coronavirus disease 2019, updates on the perioperative
management, including the use of extracorporeal membrane oxygenation, and long-term
outcomes.
Keywords
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References
- Clinical outcomes associated with computed tomography-based body composition measures in lung transplantation: A systematic review.Transplant International. 2020; 33: 1610-1625
- Skeletal muscle adiposity and outcomes in candidates for lung transplantation: A lung transplant body composition cohort study.Thorax. 2020; 75: 801-804
- What awaits on the other side: Post-lung transplant morbidity and mortality after pre-transplant hospitalization.Ann Transplant. 2020; 25 (e922641-1–e922641-8)
- Pre-transplant renal functional reserve and renal function after lung transplantation.J Heart Lung Transplant. 2020; 39: 970-974
- Frailty and aging-associated syndromes in lung transplant candidates and recipients.Am J Transplant. 2020; 21: 2018-2024
- Frailty and clinical benefits with lung transplantation.J Heart Lung Transplant. 2018; 37: 1245-1253
- Frailty phenotypes, disability, and outcomes in adult candidates for lung transplantation.Am J Respir Crit Care Med. 2015; 192: 1325-1334
- Neurocognitive changes after lung transplantation.Ann Am Thorac Soc. 2014; 11: 1520-1527
- The effect of pretransplant depression and anxiety on survival following lung transplant: A meta-analysis.Psychosomatics. 2016; 57: 238-245
- The 2018 ISHLT/APM/AST/ICCAC/STSW recommendations for the psychosocial evaluation of adult cardiothoracic transplant candidates and candidates for long-term mechanical circulatory support.Psychosomatics. 2018; 59: 415-440
- Impact of nutritional state on lung transplant outcomes.J Heart Lung Transplant. 2013; 32: 693-700
- The impact of recipient body mass index on survival after lung transplantation.J Heart Lung Transplant. 2010; 29: 1026-1033
- Usefulness of the preoperative prognostic nutritional index score as a predictor of the outcomes of lung transplantation: A single-institution experience.Clin Nutr. 2019; 38: 2423-2429
- Pulmonary rehabilitation improves survival in patients with idiopathic pulmonary fibrosis undergoing lung transplantation.Sci Rep. 2019; 9: 9347
- A 1-month physical therapy–based outpatient program for adults awaiting lung transplantation: A Retrospective analysis of exercise capacity, symptoms, and quality of life.Cardiopulm Phys Ther J. 2019; 30: 61-69
- Physical function measured prior to lung transplantation is associated with posttransplant patient outcomes.Transplant Proc. 2021; 53: 288-295
- Mobile health technology to improve emergent frailty after lung transplantation.Clin Transplant. 2021; 35: e14236
- Effect of 8-week pulmonary rehabilitation program on dyspnea and functional capacity of patients on waiting list for lung transplantation.Turk Thorac J. 2020; 21: 110-115
- Analysis of outcomes in lung transplantation.J Cardiothorac Vasc Anesth. 2019; 33: 1455-1466
- Addressing donor-organ shortages using extended criteria in lung transplantation.Ann Cardiothorac Surg. 2020; 9: 49-50
- Extended criteria donors: Closer to the truth.J Thorac Cardiovasc Surg. 2016; 152: 899-900
- Outcome of lung transplantation using grafts from donors over 65 years of age [e-pub ahead of print].Ann Thorac Surg. 2020; (Accessed August 8, 2021)https://doi.org/10.1016/j.athoracsur.2020.10.018
- National trends in extended criteria donor utilization and outcomes for lung transplantation.Ann Thorac Surg. 2021; 111: 421-426
- Utilization of marginal lung donors with low PaO2/FiO2 ratio and high body mass index.Ann Thorac Surg. 2020; 109: 1663-1669
- Clinical outcomes of lung transplants from donors with unexpected pulmonary embolism.Ann Thorac Surg. 2020; 112: 387-394
- Lungs from polytrauma donors with significant chest trauma can be safely used for transplantation [e-pub ahead of print].J Thorac Cardiovasc Surg. 2020; (Accessed August 8, 2021)https://doi.org/10.1016/j.jtcvs.2020.10.150
- Effect of lung-protective ventilation in organ donors on lung procurement and recipient survival.Am J Respir Crit Care Med. 2020; 202: 250-258
- Donor ventilation parameters as predictors for length of mechanical ventilation after lung transplantation: Results of a prospective multicenter study.J Heart Lung Transplant. 2021; 40: 33-41
- Comparison of donor scores in bilateral lung transplantation—A large single-center analysis.Am J Transplant. 2020; 21: 2132-2144
- A new lung donor score to predict short and long-term survival in lung transplantation.J Thorac Dis. 2020; 12: 5485-5494
- Transplantation after ex vivo lung perfusion: A midterm follow-up.J Heart Lung Transplant. 2016; 35: 1303-1310
- Ex-vivo lung perfusion versus standard protocol lung transplantation—mid-term survival and meta-analysis.Ann Cardiothorac Surg. 2020; 9: 1-9
- Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): A randomised, open-label, non-inferiority, phase 3 study.Lancet Respir Med. 2018; 6: 357-367
- Lung transplantation after ex vivo lung perfusion [e-pub ahead of print].Ann Surg. 2020; (Accessed August 9, 2021)https://doi.org/10.1097/SLA. 0000000000004233
- Outcomes of marginal donors for lung transplantation after ex vivo lung perfusion: A systematic review and meta-analysis.J Thorac Cardiovasc Surg. 2020; 159 (.e6): 720-730
- Extended post ex-vivo lung perfusion cold preservation predicts primary graft dysfunction and mortality: Results from a multicentric study.J Heart Lung Transplant. 2020; 39: 954-961
- Extension of donor lung preservation with hypothermic storage after normothermic ex vivo lung perfusion.J Heart Lung Transplant. 2016; 35: 130-136
- Flow-controlled ventilation during EVLP improves oxygenation and preserves alveolar recruitment.Intensive Care Med Exp. 2020; 8: 70
- Impact of the opioid epidemic on lung transplantation: donor, recipient, and discard characteristics.Ann Thorac Surg. 2019; 108: 1464-1470
- Ex vivo perfusion in lung transplantation and removal of HCV: The next level.Transpl Int. 2020; 33: 1589-1596
- A CLUE for better assessment of donor lungs: Novel technique in clinical ex vivo lung perfusion.J Heart Lung Transplant. 2020; 39: 1220-1227
- Pro-IL-1β is an early prognostic indicator of severe donor lung injury during ex vivo lung perfusion.Transplantation. 2020; 105: 768-774
- The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion.J Heart Lung Transplant. 2017; 36: 985-995
- An extracellular oxygen carrier during prolonged pulmonary preservation improves post-transplant lung function.J Heart Lung Transplant. 2020; 39: 595-603
- Coronavirus disease 2019: Implications of emerging infections for transplantation.Am J Transplant. 2020; 20: 1768-1772
- The registry of the International Society for Heart and Lung Transplantation: Thirty-second official Adult lung and heart-lung transplantation report—2015; focus theme: Early graft failure.J Heart Lung Transplant. 2015; 34: 1264-1277
- Developments in lung transplantation over the past decade.Eur Respir Rev. 2020; 29190132
- Urgently listed lung transplant patients have outcomes similar to those of electively listed patients.J Thorac Cardiovasc Surg. 2021; 161 (.e8): 306-317
- Lung Allocation score thresholds prioritize survival after lung transplantation.Chest. 2019; 156: 64-70
- Poor performance flagging is associated with fewer transplantations at centers flagged multiple times.Ann Thorac Surg. 2019; 107: 1678-1682
- Center volume and primary graft dysfunction in patients undergoing lung transplantation in the United States – a cohort study.Transpl Int. 2020; 34: 194-203
- Lung transplant center volume ameliorates adverse influence of prolonged ischemic time on mortality.Am J Transplant. 2016; 17: 218-226
- Procedural volume and survival after lung transplantation in the United States: The need to look beyond volume in the establishment of quality metrics.Am J Surg. 2016; 211: 671-676
- Factors associated with short- versus long-term survival after lung transplant [e-pub ahead of print].J Thorac Cardiovasc Surg. 2020; (Accessed August 9, 2021)https://doi.org/10.1016/j.jtcvs.2020.09.097
- Lung transplant outcomes: A review of survival, graft function, physiology, health-related quality of life and cost-effectiveness.Eur Respir J. 2004; 24: 674-685
- The registry of the International Society for Heart and Lung Transplantation: Thirty-third adult lung and heart–lung transplant report—2016; focus theme: Primary diagnostic indications for transplant.J Heart Lung Transplant. 2016; 35: 1170-1184
- Recipient age impacts long-term survival in adult subjects with cystic fibrosis after lung transplantation.Ann Am Thorac Soc. 2021; 18: 44-50
- Pre-transplant factors associated with mortality after lung transplantation in cystic fibrosis: A systematic review and meta-analysis.J Cyst Fibros. 2019; 18: 407-415
- Clinical and demographic factors associated with post–lung transplantation survival in individuals with cystic fibrosis.J Heart Lung Transplant. 2015; 34: 1139-1145
- Gender gap in cystic fibrosis mortality.Am J Epidemiol. 1997; 145: 794-803
- CF Lung transplant survival by surrogate markers for socioeconomic status.J Heart Lung Transplant. 2020; 39: S365
- Risk factors for mortality in lung transplant recipients aged ≥65 years: A retrospective cohort study of 5,815 patients in the scientific registry of transplant recipients.J Heart Lung Transplant. 2021; 40: 42-55
- The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-fifth adult lung and heart-lung transplant report—2018; Focus theme: Multiorgan Transplantation.J Heart Lung Transplant. 2018; 37: 1169-1183
- Influence of age on survival in adult patients on extracorporeal membrane oxygenation before lung transplantation.J Heart Lung Transplant. 2015; 34: 832-838
- Management of lung transplantation in the COVID-19 era—An international survey.Am J Transplant. 2020; 21: 1586-1596
- The impact of the SARS-CoV-2 pandemic and COVID-19 on lung transplantation in the UK: Lessons learned from the first wave.Clin Transplant. 2021; 35: e14210
- Current precautions and future directions in lung transplantation during the COVID-19 pandemic – a single center cohort study.Transplant Int. 2020; 33: 1453-1457
- Lung transplantation during the outbreak of coronavirus disease 2019: Early experience from china.Transplantation. 2020; 104 (-S594): S594
- COVID-19 in lung transplant recipients: A single center case series from New York City.Am J Transplant. 2020; 20: 3072-3080
- COVID-19 in lung transplant recipients: A multicenter study.Am J Transplant. 2020; 21: 1816-1824
- COVID-19 in lung transplant recipients.Transpl Infect Dis. 2020; 22: e13364
- Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient.Lancet Respir Med. 2020; 8: 1057-1060
- The anesthetic management of the first lung transplant for a patient with COVID-19 respiratory failure.J Cardiothorac Vasc Anesth. 2021; 35: 917-920
- Lung transplantation as therapeutic option in acute respiratory distress syndrome for coronavirus disease 2019-related pulmonary fibrosis.Chin Med J (Engl). 2020; 133: 1390-1396
- When to consider lung transplantation for COVID-19.Lancet Respir Med. 2020; 8: 944-946
- Twenty-year experience with extracorporeal life support as bridge to lung transplantation.J Thorac Cardiovasc Surg. 2019; 157 (.e10): 2515-2525
- Risk factors and outcomes of extracorporeal membrane oxygenation as a bridge to lung transplantation.Semin Thorac Cardiovasc Surg. 2020; 32: 772-785
- Contemporary look at extracorporeal membrane oxygenation as a bridge to reoperative lung transplantation in the United States – a retrospective study.Transpl Int. 2020; 33: 895-901
- Stratification risk analysis in bridging patients to lung transplant on ECMO: The STABLE risk score.Ann Thorac Surg. 2020; 110: 1175-1184
- Intraoperative extracorporeal membrane oxygenation and the possibility of postoperative prolongation improve survival in bilateral lung transplantation.J Thorac Cardiovasc Surg. 2018; 155 (.e3): 2193-2206
- Bilateral lung transplantation on intraoperative extracorporeal membrane oxygenator: An observational study.J Thorac Cardiovasc Surg. 2020; 160 (.e1): 320-327
- Intraoperative extracorporeal membrane oxygenation for lung transplantation in cystic fibrosis patients: Predictors and impact on outcome.J Cyst Fibros. 2020; 19: 659-665
- Utilization of extracorporeal membrane oxygenation in DCD and DBD lung transplants: A 2-year single-center experience.Transpl Int. 2020; 33: 1788-1798
- Extracorporeal membrane oxygenation versus cardiopulmonary bypass during lung transplantation: A meta-analysis.Gen Thorac Cardiovasc Surg. 2017; 66: 38-47
- The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart–lung transplantation report—2019; focus theme: Donor and recipient size match.J Heart Lung Transplant. 2019; 38: 1042-1055
- Response: The evolution of lung transplant anesthesia.J Cardiothorac Vasc Anesth. 2018; 32: e1
- The impact of anesthetic management on perioperative outcomes in lung transplantation.J Cardiothorac Vasc Anesth. 2020; 34: 1669-1680
- Anesthetic management of lung transplantation: Results from a multicenter, cross-sectional survey by the society for advancement of transplant anesthesia.Clin Transpl. 2020; 34: e13996
- Pulmonary venous flow after lung transplantation: Turbulence and high velocities.J Cardiothorac Vasc Anesth. 2020; 34: 1985-1989
- TEE for lung transplantation: A case series and discussion of vascular complications.J Cardiothorac Vasc Anesth. 2020; 34: 733-740
- Pulmonary cuff dysfunction after lung transplant surgery: A systematic review of the evidence and analysis of its clinical implications.J Heart Lung Transplant. 2019; 38: 530-544
- Pulmonary venous obstruction after lung transplantation. Diagnostic advantages of transesophageal echocardiography.Clin Transplant. 2009; 23: 975-980
- Detection of pulmonary vein stenosis by transesophageal echocardiography: Comparison with multidetector computed tomography.Am Heart J. 2007; 153: 800-806
- Preoperative anemia as a risk factor for postoperative outcomes in patients undergoing lung transplantation.J Cardiothorac Vasc Anesth. 2021; 35: 2311-2318
- Targeted bleeding management reduces the requirements for blood component therapy in lung transplant recipients.J Cardiothorac Vasc Anesth. 2017; 31: 426-433
- Rotational thromboelastometry reduces blood loss and blood product usage after lung transplantation.J Heart Lung Transplant. 2021; 40: 631-641
- Separate effect of perioperative recombinant human factor VIIa administration and packed red blood cell transfusions on midterm survival in lung transplantation recipients.J Cardiothorac Vasc Anesth. 2020; 34: 3013-3020
- The association of increased FFP:RBC transfusion ratio to primary graft dysfunction in bleeding lung transplantation patients.J Cardiothorac Vasc Anesth. 2020; 34: 3024-3032
- Operating room extubation: A predictive factor for 1-year survival after double-lung transplantation.J Heart Lung Transplant. 2021; 40: 334-342
- Impact of surgical technique and analgesia on clinical outcomes after lung transplantation.Medicine (Baltimore). 2020; 99: e22427
- Chronic pain after lung transplantation and its impact on quality of life: A 4-year follow-up.Transplant Proc. 2020; 52: 1388-1393
- Extubation outcome after spontaneous breathing trials with t-tube or pressure support ventilation.Am J Respir Crit Care Med. 1997; 156: 459-465
- Predictors of long intensive care need after lung transplantation.Clin Transplant. 2020; 35: e14152
- Interobserver variability impairs radiologic grading of primary graft dysfunction after lung transplantation.J Thorac Cardiovasc Surg. 2019; 158 (.e1): 955-962
- Preoperative risk factors for successful extubation or not after lung transplantation.J Thorac Dis. 2020; 12: 7135-7144
- Ventilation parameters and early graft function in double lung transplantation.J Heart Lung Transplant. 2021; 40: 4-11
- Is lactic acidosis after lung transplantation associated with worse outcomes?.Ann Thorac Surg. 2020; 110: 434-440
- The prognostic value of peak arterial lactate levels within 72 h of lung transplantation in identifying patient outcome.J Thorac Dis. 2020; 12: 7365-7373
- Incidence and outcomes of acute kidney injury following orthotopic lung transplantation: A population-based cohort study.Nephrol Dial Transplant. 2014; 29: 1702-1709
- Short-term and long-term outcomes of acute kidney injury after lung transplantation.J Heart Lung Transplant. 2012; 31: 244-251
- Acute kidney injury after lung transplantation: Perioperative risk factors and outcome.Transplant Proc. 2020; 52: 967-976
- Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT.J Heart Lung Transplant. 2019; 38: 493-503
- Risk assessment of chronic lung allograft dysfunction phenotypes: Validation and proposed refinement of the 2019 ISHLT classification system.J Heart Lung Transplant. 2020; 39: S64
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Published online: September 15, 2021
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