Significant mitral regurgitation (MR) is the most common valvular disease in the United
States in patients older than 75. However, many patients with severe MR are at a high
risk for surgical repair due to other significant comorbidities. Over the past decade,
many transcatheter mitral valve devices have been studied that address the different
mechanisms of MR, but only a few have received a Conformité Européene (CE) mark or
United States Food and Drug Administration (FDA) approval. The Carillon, Cardioband,
and Mitralign all received CE marking for percutaneous mitral annuloplasty, while
the Tendyne and SAPIEN 3 received a CE mark and FDA approval, respectively, for transcatheter
mitral valve replacement. Finally, the NeoChord DS 1000 received a CE mark for transcatheter
chordal repair. Each of these devices is reviewed in detail, including device indications,
performance in clinical trials, anesthetic management, intraprocedural imaging guidance,
and postprocedural complications. Although percutaneous devices will appear and disappear
from use, understanding the procedural considerations remains highly relevant, as
these key principles will apply to the next generation of transcatheter valve interventions.
Key Words
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Article Info
Publication History
Published online: May 08, 2022
Footnotes
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Dr. Rong is funded significantly by the Foundation for Anesthesia Education and Research grant number MTRG-CT-08-15-2018-Rong.
DK, PN, SP, and LR all contributed to conceptualization, writing (original draft preparation), reviewing, and editing.
Identification
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© 2022 Elsevier Inc. All rights reserved.
