In the Enhanced Recovery After Surgery era, parasternal intercostal nerve block has
been proposed to improve pain control and reduce opioid use in patients undergoing
cardiac surgery. However current literature has reported conflicting evidence about
the effect of this multimodal pain management, as procedural variations might pose
a significant bias on outcomes evaluation. In this setting, the infiltration of the
parasternal plane into 2 intercostal spaces, second and fifth, with a local anesthetic
spread under or above the costal plane with ultrasound guidance, seem to be standardized
in theory, but significant differences might be observed in clinical practice. This
narrative review summarizes and defines the optimal techniques for parasternal plane
blocks in patients undergoing cardiac surgery with full median sternotomy, considering
both pectointercostal fascial block and transversus thoracic plane block. A total
of 10 randomized trials have been published, in adjunct to observational studies,
which are heterogeneous in terms of techniques, methods, and outcomes. Parasternal
block has been shown to reduce perioperative opioid consumption and provide a more
favorable analgesic profile, with reduced postoperative opioid-related side effects.
A trend toward reduced intensive care unit stay or duration of mechanical ventilation
should be confirmed by adequately powered randomized trials or registry studies. Differences
in operative technique might impact outcomes and, therefore, standardization of the
procedure plays a pivotal role before reporting specific outcomes. Parasternal plane
blocks might significantly improve outcomes of cardiac surgery with full median sternotomy,
and should be introduced comprehensively in Enhanced Recovery After Surgery protocols.
Key Words
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Published online: July 23, 2022
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