Objective
The aim was to evaluate the effect of music on preventing delirium after coronary
artery bypass grafting, to analyze vital signs and blood gas parameters, and to determine
risk factors affecting delirium.
Design
A randomized clinical trial.
Setting
A single-center, tertiary hospital.
Participants
In total, 200 patients who underwent coronary artery bypass grafting surgery from
April 2020 to April 2021.
Interventions
A one-hour session of new-age music was administered twice a day postoperatively for
7 days using a headphone. Delirium was assessed using the Confusion Assessment Method
for the Intensive Care Unit before and after each session. Vital signs and blood gas
parameters were compared to evaluate the effect of music. All assessments were conducted
blindly by a different researcher.
Measurements and Main Results
Twelve participants who were delirium-positive were in the control group, and there
were 3 in the case group, which suggested a statistically significant effect of music
in preventing delirium (p = 0.016). The mean age of patients was 64.7 ± 7.9 years
old in the control group and 62.2 ± 7.5 years old in the case group. There was a significant
difference among the control and case groups in terms of the surgery time; surgery
time in the control group was significantly lower than in the case group (242.4 ±
42.3 v 261.6 ± 48.9, respectively; p = 0.03 < 0.05). Blood pressure and heart rate in the
case group were lower, similar to the respiratory rate and venous blood gas parameters;
Blood pressure differences were not statistically significant (p > 0.05);
Conclusion
Relaxation music, including bird, water, and wind, significantly prevents delirium
after coronary artery bypass grafting.
Key Words
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References
- Coronary artery bypass grafting versus drug-eluting stents in multivessel coronary disease. A meta-analysis on 24,268 patients.Eur J Cardiothorac Surg. 2009; 36: 611-615
- Cardiovascular risk factors and in-hospital mortality in 1258 cases of coronary artery bypass surgery in Tehran heart center.Acta Med Iran. 2012; 46: 386-390
- Multivariate analysis of factors influencing length of hospital stay after coronary artery bypass surgery in Tehran, Iran.Acta Med Iran. 2016; 54: 124-133
- Cognitive outcomes following coronary artery bypass grafting: A systematic review and meta-analysis of 91,829 patients.Int J Cardiol. 2019; 289: 43-49
- Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery.N Engl J Med. 2001; 344: 395-402
- Diagnostic and statistical manual of mental disorders: DSM-5 (5th edition).Ref Rev. 2014; 28: 36-37
- The interface between delirium and dementia in elderly adults.Lancet Neurol. 2015; 14: 823-832
- Delirium in elderly people.Lancet. 2014; 383: 911-922
- Long-term effects of postoperative delirium in patients undergoing cardiac operation: A systematic review.Ann Thorac Surg. 2016; 102: 1391-1399
- Neurocognitive and psychiatric issues post cardiac surgery.Heart Lung Circ. 2017; 26: 779-785
- Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery.Circulation. 2009; 119: 229-236
- Cerebroprotective effect of piracetam in patients undergoing open heart surgery.Ann Thorac Cardiovasc Surg. 2011; 17: 137-142
- Clinical efficacy of piracetam in cognitive impairment: A meta-analysis.Dement Geriatr Cogn Disord. 2002; 13: 217-224
- Risk factors for delirium and cognitive decline following coronary artery bypass grafting surgery: A systematic review and meta-analysis.J Am Heart Assoc. 2020; 9e017275
- The effect of music listening on acute confusion and delirium in elders undergoing elective hip and knee surgery.J Clin Nurs. 2004; 13: 91-96
- Music interventions in patients during coronary angiographic procedures: A randomized controlled study of the effect on patients’ anxiety and well-being.Eur J Cardiovasc Nurs. 2011; 10: 88-93
- Effects of patient-directed music intervention on anxiety and sedative exposure in critically ill patients receiving mechanical ventilatory support: A randomized clinical trial.JAMA. 2013; 309: 2335-2344
- Effectiveness of a music therapy intervention on relaxation and anxiety for patients receiving ventilatory assistance.Heart Lung. 1998; 27: 169-176
- Effects of music intervention on physiological stress response and anxiety level of mechanically ventilated patients in China: A randomised controlled trial.J Clin Nurs. 2010; 19: 978-987
- Prevalence and clinical characteristics of headache in a rural community in Oman.Headache. 2002; 42: 963-973
- Risk factors of neurological complications in cardiac surgery.Kardiol Pol. 2012; 70: 811-818
- The Roy adaptation model and research.Nurs Sci Q. 2009; 22: 209-211
- Mozart piano sonatas as a nonpharmacological adjunct to facilitate sedation vacation in critically ill patients.Music Med. 2013; 5: 119-127
- Acute brain failure: Pathophysiology, diagnosis, management, and sequelae of delirium.Crit Care Clin. 2017; 33: 461-519
- Music to prevent deliriUm during neuroSurgerY (MUSYC) Clinical trial: A study protocol for a randomised controlled trial.BMJ Open. 2021; 11e048270
- [Music during gastroscopy].Schweiz Med Wochenschr. 1993; 123: 1354-1358
- Reduction in salivary cortisol level by music therapy during colonoscopic examination.Hepatogastroenterology. 2004; 51: 451-453
- Cortisol and anxiety response to a relaxing intervention on pregnant women awaiting amniocentesis.Psychoneuroendocrinology. 2012; 37: 148-156
- Effects of music treatment on salivary cortisol in patients exposed to pre-surgical stress.Exp Clin Endocrinol. 1994; 102: 118-120
- Stress reduction and analgesia in patients exposed to calming music postoperatively: A randomized controlled trial.Eur J Anaesthesiol. 2005; 22: 96-102
- Emotional responses to music: Towards scientific perspectives on music therapy.Neuroreport. 2008; 19: 75-78
- The stress response to surgery and postoperative delirium: Evidence of hypothalamic-pituitary-adrenal axis hyperresponsiveness and decreased suppression of the GH/IGF-1 Axis.J Geriatr Psychiatry Neurol. 2013; 26: 185-194
- Which medications to avoid in people at risk of delirium: A systematic review.Age Ageing. 2011; 40: 23-29
- The effect of perioperative music on the stress response to surgery: A meta-analysis.J Surg Res. 2019; 244: 444-455
- The effect of perioperative music on medication requirement and hospital length of stay: A meta-analysis.Ann Surg. 2020; 272: 961-972
- Meta-analysis evaluating music interventions for anxiety and pain in surgery.Br J Surg. 2018; 105: 773-783
- The effect of music therapy on pain, anxiety and depression in patients after coronary artery bypass grafting.J Cardiothorac Surg. 2020; 15: 81
- The effect of music on anxiety and cardiovascular indices in patients undergoing coronary artery bypass graft: A randomized controlled trial.Nurs Midwifery Stud. 2015; 4: e31157
- Effects of music therapy on physiological and psychological outcomes for patients undergoing cardiac surgery.J Cardiovasc Nurs. 2006; 21: 194-200
- The effect of music on the vital signs and SPO<SUB >2</SUB>of patients after open heart surgery: A randomized clinical trial.J Maz Univ Med Sci. 2011; 21: 73-82
- The effects of music therapy on pain threshold, anxiety, distress response and hemodynamic parameters during dressing changes in burn patients.Intern Med Today. 2014; 20: 63-68
- The effect of music therapy on physiological signs of anxiety in patients receiving mechanical ventilatory support.J Clin Nurs. 2011; 20: 1026-1034
- [Effects of music therapy in intensive care unit without sedation in weaning patients versus non-ventilated patients].Ann Fr Anesth Reanim. 2007; 26: 30-38
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Publication history
Published online: September 08, 2022
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