Abstract
Objective
: The aim of this study was to assess the reproducibility of the new viscoelastic analyzer
ClotPro® and compare the parameters this system produces with the ROTEM® delta system
in patients undergoing cardiac surgery with cardiopumonary bypass (CPB).
Design
Prospective and observational study.
Setting
University Hospital.
Participants
Forty adult patients undergoing cardiac surgery with CPB.
Interventions
Correlations were calculated between ClotPro® and ROTEM® delta parameters.
Measurements and Main Results
ClotPro® showed a high reproducibility in most of the parameters of each test while
ROTEM® delta, although showed a low coefficient of variation in the parameters related
to clot firmness, showed a high variability in the coagulation times. Excellent correlations
were observed in most of the parameters of each test between ROTEM® delta and ClotPro®
(≥0.93). However, a moderate correlation was obtained between the clotting time (CT)
of the EXTEM and the EX-test (0.54). The concordance of amplitudes at different times
within each test was almost of 100% on both thromboelastometers. Regarding absolute
differences in test results, most of the measurements showed significant differences
(p < 0.0001) between both devices.
Conclusions
: ClotPro® can be used as an alternative to ROTEM® delta to evaluate coagulation function
in cardiac surgery, but specific reference ranges need to be established first.
Key Words
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Article Info
Publication History
Publication stage
In Press Accepted ManuscriptIdentification
Copyright
© 2022 Published by Elsevier Inc.
